経口避妊薬（ピル）は、重要な活性代謝産物であるデスメチルジアゼパムの除去を遅延させる。

Diazepam hanya boleh digunakan sesuai resep dan anjuran dokter. Obat ini tidak dianjurkan untuk penggunaan jangka panjang, karena bisa menimbulkan efek samping yang berat dan kecanduan (adiksi).

which makes it preferable for aged or hepatically impaired patients.30 By bypassing the prolonged-lived metabolite nordiazepam

Labor or Delivery Distinctive care has to be taken when diazepam is utilised throughout labor and shipping, as large single doses may perhaps create irregularities during the fetal coronary heart charge and hypotonia, very poor sucking, hypothermia, and reasonable respiratory melancholy during the neonates.

Decreases in clearance and protein binding, and boosts in quantity of distribution and 50 percent-lifestyle is reported in individuals with cirrhosis. In these people, a 2-fold to five-fold boost in imply half-lifetime has become described. Delayed elimination has also been reported to the Energetic metabolite desmethyldiazepam.

Furthermore, the vast majority of Newer situation-Command and cohort studies of benzodiazepine use through pregnancy, which were adjusted for confounding exposures to alcohol, tobacco along with other prescription drugs, haven't verified these findings.

低用量テオフィリン（テオドール、テオロング）はジアゼパムの作用を阻害する。

Jangan menghentikan pengobatan kecuali atas instruksi dokter. Dokter akan menurunkan dosis secara bertahap saat pengobatan perlu dihentikan.

As With all the management of intentional overdosage with any drug, it ought to be regarded as that many brokers may perhaps happen to be ingested.

You will be alarmed by how frequently the seizures happen, by how significant the seizure is, by how much time the seizure lasts, or by the colour or respiratory of the person.

Diazepam is just not encouraged from the treatment of psychotic patients and really should not be used in lieu of ideal treatment method.

Diazepam passes into breast milk. Breastfeeding is consequently not encouraged in patients receiving diazepam.

Dosage need to be individualized for maximum advantageous outcome. Whilst the standard daily dosages presented underneath will satisfy the demands of most clients, there'll be some who could demand more info larger doses. In these cases dosage need to be amplified cautiously to stay away from adverse results.

Because aged individuals usually tend to have lowered renal function, treatment really should be taken in dose assortment, and it could be valuable to watch renal functionality.